Vitamin D as an immune modulator in multiple sclerosis
نویسندگان
چکیده
منابع مشابه
P98: Vitamin-D Deficiency as a Potential Risk Factor in Multiple Sclerosis
Multiple sclerosis (MS) is a multifactorial disorder caused by the effects of several genes in combination with environmental factors. This disease is characterized by myelin loss, varying degrees of axonal pathology and inflammatory lesions. It is an important cause of disability in young adults, seen to be more prevalent in the woman, and affects 2.5 million people worldwide. Great efforts ar...
متن کاملVitamin D and multiple sclerosis: An update.
The most recent findings linking exposure to sun and vitamin D insufficiency to multiple sclerosis (MS) are reviewed. Due to insufficient sunshine and changing lifestyles, hypovitaminosis D is widespread in temperate countries. Numerous epidemiological studies have strongly suggested that sunshine and vitamin D insufficiency contributes to MS risk in these countries. Moreover, several large gen...
متن کاملVitamin D: modulator of the immune system.
1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), the active form of vitamin D, is known to regulate calcium and phosphorus metabolism, thus being a key-player in bone-formation. However 1,25(OH)(2)D(3) also has a physiological role beyond its well-known role in skeletal homeostasis. Here, we describe 1,25(OH)(2)D(3) as an immunomodulator targeting various immune cells, including monocytes, macroph...
متن کاملvitamin d and multiple sclerosis.
multiple sclerosis (ms) is a chronic demyelinating disease and also is one of the most common disabling neurological disorders in young and middle-aged adults. the main pathogenesis of ms has long been thought to be an immune mediated disorder of the central nervous system. the function of the immune system is under the influence of vitamin d which as a modulator of immune response could play a...
متن کاملVitamin D and multiple sclerosis
Multiple sclerosis (MS) is a chronic demyelinating disease and also is one of the most common disabling neurological disorders in young and middle-aged adults. The main pathogenesis of MS has long been thought to be an immune mediated disorder of the central nervous system. The function of the immune system is under the influence of vitamin D which as a modulator of immune response could play a...
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ژورنال
عنوان ژورنال: Neurologia i Neurochirurgia Polska
سال: 2019
ISSN: 1897-4260,0028-3843
DOI: 10.5603/pjnns.a2019.0015